Jules C Hancox Selected Research

Torsades de Pointes (Torsade de Pointes)

1/2021	In silico Exploration of Interactions Between Potential COVID-19 Antiviral Treatments and the Pore of the hERG Potassium Channel-A Drug Antitarget.
1/2020	QT interval prolongation and Torsades de Pointes with donepezil, rivastigmine and galantamine.
1/2020	COVID-19 Management and Arrhythmia: Risks and Challenges for Clinicians Treating Patients Affected by SARS-CoV-2.
7/2017	Solifenacin linked QT interval prolongation and torsades de pointes.
12/2016	QT interval prolongation and torsades de pointes with oxaliplatin.
8/2015	hERG potassium channel inhibition by ivabradine may contribute to QT prolongation and risk of torsades de pointes.
4/2015	hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine.
6/2014	Quetiapine, QTc interval prolongation, and torsade de pointes: a review of case reports.
4/2014	Erythromycin, QTc interval prolongation, and torsade de pointes: Case reports, major risk factors and illness severity.
1/2014	Multifactorial QT Interval Prolongation and Takotsubo Cardiomyopathy.

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Jules C Hancox Research Topics

Disease

24	Cardiac Arrhythmias (Arrythmia) 01/2021 - 01/2003
22	Torsades de Pointes (Torsade de Pointes) 01/2021 - 01/2003
12	Long QT Syndrome 01/2019 - 07/2003
10	Atrial Fibrillation 08/2020 - 04/2004
10	Short Qt Syndrome 01/2018 - 09/2006
9	Heart Failure 01/2022 - 07/2003
6	Sudden Death 11/2018 - 02/2003
4	Hypertrophy 01/2015 - 07/2003
4	Heart Diseases (Heart Disease) 04/2014 - 08/2013
3	Atrial Remodeling 01/2022 - 10/2011
3	Ventricular Tachycardia 08/2020 - 05/2005
3	Bradycardia 01/2020 - 08/2013
3	Fibrosis (Cirrhosis) 01/2020 - 10/2011
3	Acidosis 12/2019 - 01/2009
3	Ventricular Fibrillation 05/2016 - 07/2003
3	Nausea 01/2014 - 05/2013
2	Rett Syndrome (Rett's Disorder) 05/2022 - 10/2019
2	Cardiotoxicity 01/2021 - 05/2004
2	Seizures (Absence Seizure) 01/2020 - 05/2010
2	Heart Arrest (Cardiac Arrest) 01/2018 - 05/2016
2	Cardiac Sudden Death (Sudden Cardiac Arrest) 06/2014 - 01/2013
2	Hypokalemia 06/2014 - 08/2013
2	Vomiting 01/2014 - 05/2013
1	Respiratory Tract Infections (Respiratory Tract Infection) 09/2021
1	COVID-19 01/2021
1	Ventricular Premature Complexes (Premature Ventricular Contraction) 01/2021
1	Epilepsy (Aura) 01/2020
1	Alzheimer Disease (Alzheimer's Disease) 01/2020
1	Critical Illness (Critically Ill) 01/2020
1	Channelopathies 01/2019
1	Sick Sinus Syndrome 09/2017
1	Ischemia 09/2017
1	Eye Diseases (Eye Disease) 01/2017
1	Coronary Artery Disease (Coronary Atherosclerosis) 04/2015

Drug/Important Bio-Agent (IBA)

14	Pharmaceutical PreparationsIBA 01/2021 - 06/2003
9	Potassium Channels (Potassium Channel)IBA 01/2021 - 07/2003
8	PotassiumIBA 01/2022 - 10/2008
8	Anti-Arrhythmia AgentsIBA 08/2020 - 06/2003
7	Ether (Diethyl Ether)IBA 01/2018 - 07/2003
6	Ion Channels (Ion Channel)IBA 01/2022 - 04/2004
4	Anti-Bacterial Agents (Antibiotics)IBA 09/2021 - 04/2006
4	IvabradineIBA 01/2017 - 04/2015
4	Clarithromycin (Biaxin)FDA LinkGeneric 04/2014 - 08/2013
3	MacrolidesIBA 09/2021 - 11/2013
3	Azithromycin (Zithromax)FDA LinkGeneric 09/2021 - 10/2013
3	Quinidine (Chinidin)FDA LinkGeneric 01/2018 - 09/2006
3	Disopyramide (Norpace)FDA LinkGeneric 01/2017 - 09/2006
3	Ranolazine FDA Link 10/2016 - 12/2010
2	Sodium Channels (Sodium Channel)IBA 05/2022 - 06/2003
2	ElectrolytesIBA 01/2020 - 01/2020
2	Erythromycin (Erycette)FDA LinkGeneric 01/2020 - 04/2014
2	Biomarkers (Surrogate Marker)IBA 11/2018 - 08/2008
2	Adenosine Triphosphate (ATP)IBA 09/2017 - 12/2012
2	salicylhydroxamic acid (SHAM)IBA 03/2017 - 10/2011
2	Cytochrome P-450 CYP3AIBA 06/2014 - 04/2014
2	Citalopram FDA LinkGeneric 01/2014 - 10/2013
2	Protein Isoforms (Isoforms)IBA 09/2013 - 06/2007
2	Methadone (Dolophine)FDA LinkGeneric 09/2013 - 08/2013
2	Dronedarone FDA Link 04/2012 - 04/2004
2	Antipsychotic Agents (Antipsychotics)IBA 12/2006 - 02/2003
1	remdesivirIBA 01/2021
1	Atazanavir Sulfate (Reyataz)FDA Link 01/2021
1	Antiviral Agents (Antivirals)IBA 01/2021
1	lopinavir-ritonavir drug combination (Kaletra)FDA Link 01/2021
1	HydrocarbonsIBA 01/2021
1	favipiravirIBA 01/2021
1	phenanthreneIBA 01/2021
1	Rivastigmine (Exelon)FDA LinkGeneric 01/2020
1	Donepezil (Aricept)FDA LinkGeneric 01/2020
1	Pentylenetetrazole (Metrazol)IBA 01/2020
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2020
1	Anticonvulsants (Antiepileptic Drugs)IBA 01/2020
1	GadoliniumIBA 01/2020
1	Galantamine (Galanthamine)FDA LinkGeneric 01/2020
1	CannabinoidsIBA 01/2020
1	Protons (Proton)IBA 12/2019
1	sarizotanIBA 10/2019
1	Oxytocin (Pitocin)FDA LinkGeneric 01/2019
1	Hormones (Hormone)IBA 01/2019
1	ProlactinIBA 01/2019
1	NS 3623IBA 01/2018
1	Acetylcholine (Acetylcholine Chloride)FDA Link 09/2017
1	Solifenacin Succinate FDA Link 07/2017
1	Cyclic AMP-Dependent Protein Kinases (cAMP-Dependent Protein Kinase)IBA 03/2017
1	Oxaliplatin (Eloxatin)FDA LinkGeneric 12/2016
1	triadinIBA 05/2016
1	3-(2-carboxyindol-3-yl)propionic acidIBA 01/2016
1	Flufenamic AcidIBA 01/2016
1	Angiotensin Receptor AntagonistsIBA 01/2015
1	Hydralazine (Apresoline)FDA LinkGeneric 01/2015
1	CalciumIBA 01/2015
1	candesartanIBA 01/2015
1	Angiotensin Receptors (Angiotensin II Receptor)IBA 01/2015

Therapy/Procedure

4	Drug Therapy (Chemotherapy) 01/2018 - 05/2013
3	Therapeutics 01/2020 - 04/2012
3	Implantable Defibrillators (Implantable Cardioverter-Defibrillator) 01/2018 - 04/2004
2	Defibrillators (Defibrillator) 01/2018 - 05/2016
2	Resuscitation 01/2018 - 07/2003
1	Polypharmacy 01/2020
1	Ligation 03/2017